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Although not everyone needs a therapeutic after an injurylimiting the damage after the first concussion may lessen the side effects from the next. More funding needed Korinek says most investors he has talked with understand the commercial potential for concussion therapeutics but need to know that definitive trials can be conducted in heterologous populations, how expensive they will be, and whether big pharma is willing to acquire emergent programs

[2] NNMT transfers a methyl group from S-adenosyl-L-methionine (SAM) to nicotinamide

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The proportions of patients experiencing treatment-related adverse events in the three treatment groups (20 mg, 40 mg, and placebo groups) were similar at 86.5%, 88.0%, and 85.3% respectively