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doi: 10.1152/ajpregu.00428.2006 110 AfonsoRALauttWWSchaferJLegareDJOliveiraAGMacedoMP

GHK-Cu and retinoids like tretinoin are both powerful actives, but using them together at the same time can cause skin irritation or reduce their effectiveness

Moore, J., Goodson, N., Wicks, P

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