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They further note that, given peripherally, BPC 157 counteracts central dopamine-system disturbances and induces serotonin release in the substantia nigra, and that it can heal various wounds and instantly recover disturbed lower esophageal and pyloric sphincter pressure in rats with long-standing esophagitis

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To the best of our knowledge, this represents the first real-world experience with Polmacoxib 2 mg in this patient population