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Enhancing GSH, mainly through NAC, GSH precursors rich in cysteine (whey protein, whey protein isolate rich in cysteine) or pro-GSH compound administration, becomes a potential treatment option for inflammatory diseases by reducing oxidative stress and cytokine expression especially in diabetic patients that also are at risk of more severe COVID-19 disease (299)

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and others, as well as cigarette smoking and smokeless tobacco are capable of degrading glutathione to form toxic hydrogen sulphide within the periodontal cells

This is especially important for compounded or injectable preparations