doi: 10.1128/spectrum.02256-22 90 SunKYanCDaiXShiYLiFChenLet al
however, T-cell receptor (TCR)-stimulated activation increases the expression of the Myc transcription factor, glutamine transporters (SLC38A1, SLC38A2), and glutaminolysis-related enzymes (GLS, GLUD1, GOT, GPT) to meet bioenergetic and biosynthetic requirements, resulting in T-cell proliferation 130,131,132,133
Additional important safety considerations include: risk of pancreatitis (patients should seek immediate medical attention for severe abdominal pain)
The benzyl alcohol preservative helps prevent bacterial growth inside the vial, allowing the solution to remain stable for multiple withdrawals when handled using sterile technique