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Titration: Provider-Directed, Flat-Rate by Design The flat pricing model at every dose tier removes the structural incentive to push patients toward higher and more expensive doses

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The anti-amyloid antibodies of the 2020s, the first drugs ever to bend the course of the disease at all, did it the hard way: enormous multi-country trials with pre-specified cognitive endpoints, full publication in the New England Journal of Medicine and JAMA , and a brutal public fight over whether their modest benefit was even worth the brain-swelling risk

Aftercare can include ongoing therapy, support groups, family support, and sober routines