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The Retatrutide Phase 2 trial (published 2023) enrolled 338 adults with BMI of 30 or higher, or BMI of 27 or higher with at least one weight-related comorbidity

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Your doctor may increase your dose by 2.5 mg increments to 7.5 mg, 10 mg, 12.5 mg or 15 mg once a week if you need it

Breastfeeding Safety and GLP-1 Medication Considerations Lactating mothers require medications with established infant safety profiles, since even low-concentration breast milk transfer creates potential exposure during critical developmental windows