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Ferroptosis with characteristic accumulation of oxidized phospholipids (or their breakdown products) in myocardial and renal tissue is responsible for ischemia-reperfusion injury, which is a detrimental factor for cardiac damage and MODS in COVID-19 patients 499

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Apoptosis - inducing factor mitochondria - associated 2 (AIFM2), a lipid - binding protein, was recognized as a novel anti - ferroptosis gene, Bersuker et al