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Changes in taste are a documented sensory side effect of GLP-1 medications that stem from the way the brain and gut process reward, cravings, and satiety

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However, in a more recent randomized, placebo-controlled study in 102 subjects, daily supplementation with 600 mg of lipoic acid (+/- 800 mg of vitamin E [-tocopherol]) for 16 weeks had no effect on fasting blood glucose, fasting blood insulin, or a measure of insulin resistance called the homeostatic model assessment of insulin resistance (HOMA-IR) index (59)

2.2.3 The role of the cytokine network in complications Cytokines play a double-edged sword role in the development of postoperative complications