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Brief exposure to room temperature is usually fine, but high heat (above 86F) can cause the peptide to break down quickly

A vial pulled from the freezer, partially used, refrozen, and pulled again has experienced multiple freeze-thaw cycles that progressively damage the peptide structure, as noted in Bachems pharmaceutical handling and storage guidelines for peptides, which outline how thermal cycling degrades peptide integrity at the molecular level even before visible changes occur

Treatment typically begins with lower doses (200 mcg) and increases based on clinical response

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