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We were surprised to find there were no major differences in revascularization or in-stent restenosis despite our initial inclination that GLP-1RAs may reduce incidences of these cardiovascular events, said Moses Sghayyer, MD, Tinsley Harrison Internal Medicine resident at the University of Alabama at Birmingham in Birmingham, Ala., and lead author of the study

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In addition, the activation of GLP-1R by exendin-4 increased cAMP accumulation and reduced cytokine production in IELs