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The broader picture is one in which MOTS-c addresses a gap that many other longevity interventions leave unfilled: the mitochondrial signaling decline that is simultaneously a cause and consequence of metabolic aging

Initially, we assessed the levels of important ferroptosis-associated proteins and found that ACSL4 and LPCAT3 levels increased early after SCI, while GPX4 and FTH1 levels decreased (Fig

10.1182/blood.2022018159 90 XiaoX.MoschettaG