2.5 mg retatrutide results 3-Month Results: Weight Loss Clinical Data (2026) Retatrutide vs Tirzepatide (2026): Differences

[1] [2] Symptoms that have been described include: Injection site reactions : redness, swelling, itching, or mild bruising at the site of subcutaneous administration consistent with class effects seen with semaglutide and tirzepatide (see eMC SmPCs for Wegovy, Ozempic, and Mounjaro for comparator data) Pruritus or urticaria : patchy or widespread skin itching or redness, which may reflect a hypersensitivity response again consistent with known class effects of GLP-1-based therapies [17] Generalised skin sensitivity : heightened sensitivity to touch, temperature, or pressure beyond the injection site

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Never freeze reconstituted peptide solutions

In Phase 2 clinical trials, patients showed progressive, dose-dependent weight loss of up to 24.2% of body weight with a 12 mg weekly dose