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Additionally, Chinese medicine has been found to have a significant effect on probiotics such as the Rikenellaceae_RC9_gut_group and g_Bifidobacterium , and may also influence the production of metabolites including Imidazoleacetic acid, DL-glutamine, 2-deoxy-D-glucose, and L-pyroglutamic acid by promoting the growth of beneficial bacteria to modulate the Th17/Treg immune response (Ruan et al., 2016)

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