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[35] Long-term potentiation [edit] Long-term potentiation, commonly referred to as LTP, is an increase in synaptic response following potentiating pulses of electrical stimuli that sustains at a level above the baseline response for hours or longer

This imbalance significantly disrupts the basal ganglia circuitry, leading to the hallmark motor symptoms of PD, including tremors, bradykinesia, and rigidity

This will help prevent any fluctuations in temperature that could compromise the medication