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However, NT69L attenuated baseline alcohol consumption and preference in wildtype as well as in NTS2 KO mice (Lee et al., 2011)

Parents were told how to measure the dose using measuring spoons provided by study personnel

This randomised, double-blind, placebo-controlled trial enrolled 706 adults with overweight or obesity (BMI 27 or above) across multiple dose groups, running over 26 weeks

Research protocols employ diverse approaches including isolated mitochondria preparations, permeabilized muscle fiber respirometry, stable isotope tracers for metabolic flux analysis, cellular bioenergetics assays (Seahorse), and in vivo metabolic phenotyping in rodent models