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Manage perioperative risks

These benefits occur through blood pressure reduction (1-5.4 mmHg lower systolic blood pressure) 10 , improved vascular function, and direct effects on the heart

Notably, our previous research highlighted how individuals with T2D initiate GLP-1 RA treatment at lower A1c and BMI levels in more recent years (Cartwright et al., 2024), reflecting a trend toward broader and more accessible use of these drugs

Further longer term studies of normal and genetically modified rodents are clearly warranted