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Caution is warranted in patients with a history of pancreatitis, severe gastrointestinal disease including gastroparesis, or diabetic retinopathy

Ahmadian E, Babaei H, Nayebi AM et al (2016) Venlafaxine-induced cytotoxicity towards isolated rat hepatocytes involves oxidative stress and mitochondrial/lysosomal dysfunction

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Furthermore, access to GLP1-RAs is a major issue for uptake remaining relatively low despite the high efficacy of these medications (Rodriguez et al., 2025)