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A 2025 systematic review of BPC-157 in orthopedic applications confirmed improved structural, functional, and biomechanical outcomes across muscle, tendon, ligament, and bone injuries in 36 studies

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Pregnancy and breastfeeding : do not start glutathione or NAC supplements without medical advice, as evidence for routine supplementation in these groups is limited (despite medicinal use of NAC for paracetamol overdose under specialist supervision)