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Summary (Summary written by Claude, Sonnet 4.6, Anthropic) This chapter describes the pentose phosphate pathway (PPP), a cytosolic branch of glucose metabolism that diverges from glycolysis after the formation of glucose-6-phosphate and serves two principal biosynthetic functions: generation of NADPH for reductive biosynthesis and antioxidant defense, and generation of ribose-5-phosphate for nucleotide and nucleic acid synthesis
This work was made possible by grant support from the Israel Science Foundation (ISF
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