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112 Decreased BBB permeability and upregulated expression of tight junction proteins were observed in germ-free adult mice

10.1038/s41467-018-06331-w Nat

[DOI] [PubMed] [Google Scholar] 122.Lau J., Bloch P., Schffer L., Pettersson I., Spetzler J., Kofoed J., Madsen K., Knudsen L.B., McGuire J., Steensgaard D.B., et al

Numerous reports substantiate that CSCs play a crucial role in driving tumor initiation, treatment resistance, recurrence, and metastasis ( Figure 3A )