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However, understanding when high B12 levels may become problematic helps ensure safe, evidence-based supplementation under appropriate medical supervision

Estrogens, tri-iodothyronine, and dexamethasone are the nuclear hormones that have been tested

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While the mechanism of action of mecobalamin against amyotrophic lateral sclerosis (ALS) is not known, it has been suggested in non-clinical research that mecobalamin may have efficacy through a neuroprotective effect and regeneration of nerve axons