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Individual tolerance may vary during initial treatment due to gastrointestinal side effects, but this relates to personal sensitivity rather than a specific drug-food interaction
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Certain genetic variants in the GLP-1 receptor (GLP1R rs6923761), glucose-dependent insulinotropic polypeptide receptor (GIPR rs1800437), and appetite-regulation genes like FTO and MC4R may influence individual semaglutide efficacy and side-effect tolerance
Unlike these multi-dose pens, the Wegovy 7.2mg pen is single use and comes with a pre-attached needle that is only exposed during the injection process
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