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DNP was later studied at Stanford in the 1930s, where scientists warned of the dangers of DNP alongside reports of its effectiveness in weight loss

More importantly, we found that the causal effect of ISI on MASLD was independent of BMI, which means the effects of GLP-1R-based agonists on MASLD were partly independent of their weight-loss effect

[5] [1] Whilst most patients experience mild to moderate symptoms that improve over time as the body adjusts to the medication, some individuals find these effects troublesome enough to affect their quality of life