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doi: 10.1001/jama.2015.13480

El sistema nervioso central (SNC) recibe cierta informacin perifrica capaz de regular el equilibrio energtico del individuo a travs de seales metablicas, neuronales y endocrinas

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In experimental models, it is used to investigate melanocortin mediated CNS pathways and downstream signaling, with a mechanistic focus distinct from direct peripheral vasodilatory (blood flow) mechanisms