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This method has a low encapsulation efficacy and high frequency can degrade the compounds that are to be encapsulated

doi:10.2147/DMSO.S254555

Clinical studies, such as the STEP trials, have shown that adults using semaglutide GLP-1 at the recommended dose (2.4 mg weekly) can lose an average of about 15% of their initial body weight over 68 weeks when combined with healthy lifestyle changes