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However, efficacy in clinical studies has been disappointing, possibly because excessive chronic stimulation is associated with receptor internalisation, and some agents have disturbed liver function [25, 26]

What are GLP-2 analogs actually prescribed for according to the article

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Fc-GLP-1 also improved the fatty liver phenotype in DIO mice, confirming the efficacy of this GLP-1R agonist in obese and non-obese hepatic dysfunction linked to NAFLD