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The WHO guidelines will lower the stigma around obesity, says Rizo, and likely improve access to glucagon-like peptide-1 (GLP-1) drugs, such as Wegovy and Zepbound, which were originally intended to treat diabetes but have demonstrated to be highly effective for weight management

Furthermore, oral administration is more prone to experiencing adverse events (AE) that are not listed in the product labeling

By targeting three complementary hormone receptors simultaneously, these investigational therapies aim to improve multiple aspects of metabolic health rather than focusing solely on glucose control

0.5 kg, p = 0.001) and bone fractures requiring surgery or hospitalization in the pioglitazone group (5% vs