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Initial Treatment: For severe cases, doses can be 1000 mcg to 2000 mcg

Important note: The serum test measures total vitamin B12, including both the active (holo-transcobalamin) and inactive forms

The degradation process of tryptophan in KP produces a variety of neuroactive metabolites with amino acid-like structures, such as an N-methyl-D-aspartate (NMDA) receptor agonist quinolinic acid (QA), and a neuroprotective NMDA receptor agonist kynurenic acid (KYNA)