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Research suggests that oxidative stress contributes to age-related decline in ovarian reserve, as well as conditions such as endometriosis and polycystic ovary syndrome (PCOS), which are associated with infertility

While histamine itself is relatively stable chemically, the broader biogenic amine profile of oxidized coffee and the overall degradation of the chemical environment that results from poor packaging creates conditions that may be less predictable for sensitive consumers than freshly roasted, properly preserved coffee

Warren K

It can give rise to hyperpigmentation, blemish and uneven dark skin tone