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The Cleveland Clinic explains that GLP-1 agonist medications like Ozempic and Mounjaro work by triggering your pancreas to release more insulin, adding: The slowed digestion also helps decrease blood sugar spikes. These factors can play into appetite, digestion, the metabolization of food into energyand in turn, possibly weight loss

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When people lose weight quickly, they may lose a mix of fat, water, and lean mass

GLP-1 Medication Semaglutide is a GLP-1 medication that mimics the hormone that tells the brain its finished eating, suppressing hunger and decreasing appetite