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GSH scavenges a wide range of ROS ( OH, H 2 O 2 , 1 O 2 ), and due to the very low value of electron reduction potential of the GSSG/GSH redox couple ( E = 264 mV at pH = 7.4) is GSH able to regenerate several important antioxidants, such as radicals of vitamins E and C back to their active non-radical forms (Jones 2002) (Fig

Hippocampal cell culture preparation Hippocampal neurons (2xl0 5 cells per square cm) were cultured from PI Sprague Dawley rats on plates coated with poly-L-lysine from Sigma (St

Ozcan U, Cao Q, Yilmaz E, Lee AH, Iwakoshi NN, Ozdelen E, et al