PPAR-, ER, AR, farnesoid X receptor, FXR, pregnane X receptor, PXR) [261,262,263,264,265] was demonstrated, which raises concern over potential long-term adverse health effects
GLP-1 medications have also been associated with: Worsening of diabetic retinopathy Exacerbation of age-related macular degeneration Optic nerve complications, including NAION These risks dont mean you should stop taking your medication, but they do show why its important to have an eye exam before starting and regular follow-up exams while on treatment
These differences in adverse event profile may be in part driven by a differing impact on estradiol
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