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Exogenous antioxidants: Vitamin C Vitamin E Carotenoids Polyphenols Zinc Selenium Endogenous antioxidants: Superoxide dismutase (SOD) Catalase (CAT) Glutathione peroxidase (GPx) Paraoxanase Glutathione S -transferase (GST) Glutathione Lipoic acid Bilirubin Melatonin Ubiquinol Uric acid Ferritin Transferrin Interventions Interventions below may vary depending on which genes in the oxidative stress panel are impacted

doi: 10.1016/j.atherosclerosis.2015.10.091 93 OhashiK.BurkartV.FlohS.KolbH

Research has demonstrated that the accumulation and deposition of MSU crystals in the joint cavity can enhance oxidative stress, releasing large quantities of oxidants such as ROS, nitric oxide (NO) and malondialdehyde (MDA), while suppressing the activity of antioxidants such as superoxide dismutase (SOD) and glutathione (GSH)

(1) The authors suggested that both formulations appeared to produce a positive response regarding hair growth in the animals