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PRP is an autologous blood fraction that contains a high concentration of platelets and their associated growth factors (GFs), including platelet-derived GF (PDGF), vascular endothelial GF (VEGF), transforming GF- (TGF- ), and epidermal GF (EGF) [6] (Fig

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Lin discovered that oxidative stress might decrease the expression of the histone-lysine N-methyltransferase EZH2 and the level of lysine 27 of the histone H3 protein in GCs while increasing the expression of Interleukin-1 receptor type 2 to suppress ovulation signals (77)