Protein Intake: Protein helps preserve muscle and promotes satiety
Meet our doctors Last reviewed: 03 Jul 2026 Sources Foundayo, LillyDirect [accessed 29 June 2026] Mounjaro KwikPen 10mg solution for injection in prefilled pen, emc [accessed 29 June 2026] Nevolat 6 mg/ml solution for injection in prefilled pen, emc [accessed 29 June 2026] Oral Semaglutide at a Dose of 25 mg in Adults with Overweight or Obesity, The New England Journal of Medicine (NEJM) [accessed 29 June 2026] Orforglipron, an Oral Small-Molecule GLP-1 Receptor Agonist for Obesity Treatment, NEJM [accessed 29 June 2026]
Tiredness may result from multiple factors including direct medication effects, inadequate caloric or nutritional intake due to reduced appetite, dehydration from gastrointestinal side effects, metabolic adaptation to weight loss, and blood sugar fluctuations in patients taking diabetes medications
Step 1: Complete Pivotal Trials (Mid-2026) Eli Lilly needs final data from TRIUMPH-1 (2,300 obesity patients) and TRIUMPH-2 (1,000 type 2 diabetes patients)