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29 Statistical Analysis Primary Outcomes of the Studies Power Calculation For the STEP 1 to STEP 4 trials, the power calculations were based on the randomization ratio, the 5% significance level, the statistical tests chosen for continuous outcomes (t-test on the mean differences assuming equal variances) and binary outcomes (Pearson chi-square test for 2 independent proportions), and permanent discontinuations of 20% (5% for STEP 4), with 60% of those retrieved at week 68 (based on study NN9536 to 4153)

However, persistent or unexplained changes might indicate a more serious issue

Benefits may include: Easy-to-administer injections (once weekly) Low initial dose, which helps to minimize side effects Patients can lose up to 20% of their excess weight, according to clinical trials Lowered risk of weight-related health problems, including hypertension, high cholesterol, and sleep apnea Enhanced glycemic control, minimizing the risk of diabetic retinopathy Am I a good candidate for Tirzepatide

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