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2.5 Biological activities of collagen-based supplements Collagen-based supplements exert a broad spectrum of biological activities, primarily attributed to the release of bioactive peptides during enzymatic hydrolysis and gastrointestinal digestion (Table 1) [24, 37, 63]

Despite the consensus that UA released as a result of cell death in both species acts as an inflammatory trigger 3,4 , it is possible that pathological concentrations found in mice could not induce an immune response in human cells