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415 Antidepressants target astrocytes Antidepressant drugs include (i) selective serotonin reuptake inhibitors (SSRI), of which fluoxetine (Prozac) is the most popular, (ii) serotonin/noradrenaline reuptake inhibitors (SNRI), (iii) tricyclic antidepressants, (iv) inhibitors of monoaminoxidase, (v) lithium, and (vi) ketamine

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The augment in extracellular lactate has also been reported to provide an immune-conducive environment for tumor cells by reducing the activation and function of dendrites and T cells (269, 270)

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