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Patients inadequately controlled on sitagliptin monotherapy If therapy with a combination tablet containing sitagliptin and metformin is considered appropriate for a patient inadequately controlled on sitagliptin alone, the recommended starting dose of Janumet is 50 mg sitagliptin/500 mg metformin hydrochloride twice daily

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Insurance plans typically categorize medications into different tiers, and each tier comes with a different cost-sharing requirement (copays or coinsurance)

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