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Some studies suggest combining GLP-1 therapy with metformin may provide additive benefits
Healthy Lifestyle Although GLP-1 reduces appetite and promotes weight loss, effectiveness depends on combination with "a healthy diet and regular exercise." GLP-1 injections are contraindicated for individuals who: "You should ALWAYS consult with your medical provider to determine if GLP-1 injections are safe and appropriate." GLP-1 injections present "a promising option for those seeking effective weight loss when supported with lifestyle changes." Healthcare provider consultation remains essential before initiating treatment
doi: 10.1038/nrendo.2015.231
Individual results will vary based on factors including age, baseline weight, metabolic health, consistency of use, lifestyle factors, genetic factors, current medications, and other individual variables
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