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Discussion Causality assessment and differential diagnosis We applied the Roussel Uclaf Causality Assessment Method (RUCAM) to evaluate the causal relationship between each suspected drug and DILI

Genitourinary There is growing evidence that ketamine can cause urologic complications, although this is primarily from animal studies and chronic recreational use by humans

Oxidative stress is a major contributor to gastrointestinal mucosal diseases, with the overproduction of ROSs implicated in the development of these conditions [157,158]

Journal of Applied Physiology, 109(3), 711718