can i lower my dose of tirzepatide Dosage Guide and Chart for Weight Loss Staying at lower dose? :

Genetic Predispositions in Peptide Pathways: Why Your DNA Influences Response Genetic variation in GLP-1 receptor (GLP1R rs6923761), GIPR (rs1800437), FTO (rs9939609), and MC4R (rs17782313) genes affects appetite regulation, baseline metabolic rate, and medication response

While it does not directly affect prolactin or oxytocin, changes in body weight, blood sugar, and insulin levels might influence overall hormone balance

found that GLP-1RA medications may have broader heart and metabolic effects, as well as reduce inflammation in addition to weight loss and glucose control in high-risk populations

In clinical trials, people taking semaglutide lost an average of 15% in a little over a year (even more for those taking Wegovy HD), while those on tirzepatide lost an average of 21% in roughly the same time