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What patients do report, usually transiently, includes a brief injection-site reaction, mild flushing across the face or chest for a few minutes after injection, and occasional tingling in the hands or feet that can signal the dose needs adjusting
Safety Considerations and Provider-Supervised Decision Making Dual GLP-1 and GIP agonism increases the risk of gastrointestinal side effectsnausea, vomiting, constipation, and pancreatitis riskwithout clear clinical evidence of enhanced outcomes
The disease is rare in Asia and Africa, where most people eat high-fiber diets
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