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However, further investigations reveal that VDR signaling is indispensable for the development and function of certain tissue-specific or unconventional T cell subsets, including invariant natural killer T (iNKT) cells and CD8 intraepithelial lymphocytes (IELs) [155, 156]

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As a canonical PRR, NLRP3 constitutes the structural and functional core of the inflammasome complex [45]