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however, follicular cell hyperplasia can lead to false-positive results

In those trials, patients achieving LDL concentration below 30 mg/dl did not show any deterioration of their cognitive processes in comparison with those with higher LDL concentration

Current theories concerning disease pathogenesis include an imbalance between protease and anti-protease activity, induced apoptosis of alveolar cells through deregulation of pathways involved in oxidative stress, chronic inflammation, and aberrant tissue remodeling that lead to the destruction of the extracellular matrix (ECM) in the lung [3, 4]

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