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In addition to Ca 2+ , S100A2 also binds to Zn 2+ with higher affinity, and the binding affinity of S100A2 to calcium is significantly reduced upon binding to zinc ( 2+ - and Zn 2+ -ions have opposite effects on the stability of S100A2, with Ca 2+ acting as a protein stabilizer and Zn 2+ as a protein destabilizer ( Figure 2 S100A2 is a member of the S100 EF-hand calcium-binding family found in mammary epithelial cells and other organs or tissues, including the lungs, kidneys, liver, and prostate gland ( Many factors can regulate the distribution and expression levels of S100A2

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Although microneedle technology offers superior patient compliance compared to traditional drug delivery systems, it still faces certain limitations [186]

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10.1007/s00425-007-0586-z Summary Keywords bacterium, fungus, glutathione S-transferase, oxidative stress, plant pathogen, salicylic acid, virus, WRKY Citation Gullner G, Komives T, Kirly L and Schrder P (2018) Glutathione S-Transferase Enzymes in Plant-Pathogen Interactions

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