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7 methodologically sound randomized controlled trials were identified involving 660 participants with hepatic encephalopathy, totaling 249 with subclinical hepatic encephalopathy, 189 with West Haven grade 1, 162 with West Haven grade 2 and 60 with West Haven grade 3

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Their use is not without controversy and their advantageous therapeutic effects are sometimes overshadowed by reported negative effects

For instance, comparable shares of women (56%) and men (51%) who are familiar with these drugs think they are good options for weight loss for people with obesity or a weight-related health condition