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In addition, fasting-induced improvements in insulin sensitivity and reductions in systemic inflammation may indirectly support gonadal steroidogenesis by restoring optimal Leydig cell responsiveness, which is crucial for testosterone production [58]

However, products that are approved in an expedited fashion may not have enough initial data to support claims that the product will provide meaningful therapeutic benefit in the space

It affects approximately 10 percent of individuals of reproductive age and is a leading cause of chronic pelvic pain, dysmenorrhea, dyspareunia, and infertility

ACKNOWLEDGEMENTS The authors responsibilities were as followsJS: conceived of and drafted the first and subsequent drafts of the manuscript