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PlexusDx also offers the Precision Peptide Genetic Test ($99 add-on after your first month) to identify which peptide-pathway variants may influence your response to tirzepatide

If you are unable to obtain coverage for Ozempic from your insurance plan, you can try to obtain coverage for alternative medications such as Wegovy (semaglutide), Mounjaro (tirzepatide), Zepbound (tirzepatide) or Trulicity (dulaglutide)

For example, extracellular proteases, such as HGFA, matriptase, and MMP-2, can cleave and transform HGFs into their active biological state, thereby facilitating the release of HGF [55]

The dominant mechanism is the ratio shift between estrogen (which protects hair follicles) and androgens (which can drive scalp follicle miniaturization in genetically susceptible women)